Work

Structures of the PI3Kα/KRas complex on lipid bilayers reveal molecular mechanisms of PI3Kα activation

Year: 2026

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2026.06.010

Authors: Hayarpi Torosyan, Michael D. Paul, Brigitte G. Meyer, Allison Maker, Natalia Jura, Kliment A. Verba

Institution: University of California, San Francisco

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Queensland Brain Institute, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences

Awards: Molecular and Cellular Basis of Cardiovascular Disease, The Cancer Cell Map Initiative v2.0, Structural and Functional Studies of HER Receptors

OpenAlex ID: W7165918339

FWCI: 12.3

Cites: 71

Cited by: 9

Related to: 10