Geminivirus-Induced Reprogramming of Plant Defense Mechanisms: Molecular Insights and Research Frontiers
Year: 2026
Type: review
Abstract: Geminiviruses employ multifunctional protein ammunition to evade robust plant defense pathways. Key viral proteins effectively manipulate host signaling mechanisms to create a permissive environment for viral replication. Rapid evolutionary adaptation of geminiviruses, synergized by the proliferation of insect vectors, creates a challenge for effective disease control. Current plant resistance against geminiviruses primarily relies on antiviral RNA silencing and the localized cell death mechanism as an outcome of the hypersensitive response. To win the escalating arms race between geminivirus manipulation and subsequent plant counteracting strategies and effectively restrict viral invasion, these defense strategies need to be updated or supplemented with novel engineering approaches. In this review, we provide a critical contemporary understanding of viral reprogramming pathways and host counter-defense responses that provide new avenues to improve plant immunity against geminiviruses.
Source: Annual Review of Virology
Authors: Namisha Sharma, Susmita Sett, Manoj Prasad
Language: English
Topic: Plant Virus Research Studies
Subfield: Plant Science
Domain: Life Sciences
SDG: Zero hunger
Open Access status: hybrid
OpenAlex ID: W7165951219