Work

Cutting Edge: Motion-Tracking Brillouin Microscopy for Corneal Mechanical Evaluation

Year: 2026

Type: article

Abstract: In Brief Motion-tracking Brillouin microscopy enables direct, depth-resolved, spatially precise assessment of corneal mechanics, revealing focal anterior weakening as the earliest signature of keratoconus. By accurately identifying subclinical disease, this custom-built research device offers a unique, mechanics-based approach to refractive screening, ectasia risk assessment, and early keratoconus detection.

Source: Cornea

DOI: 10.1097/ico.0000000000004215

Authors: Bianca N. Susanna, Bassel Hammoud, Barbara A. L. Dutra, Hongyuan Zhang, Giuliano Scarcelli, J. Bradley Randleman