In-vitro mineralization of borosilicate glasses and accompanying evolution of porous architecture
Year: 2026
Type: article
Abstract: Sol-gel process proved to be an effective approach to synthesize borosilicate-based bioactive glasses with significant crystallization induced during devitrification verified by Na2CaSiO4 phase. A progressive growth of hydroxyapatite (HA) phase in the size range of 17–26 nm was observed. Fourier transform infra-red (FTIR) spectroscopy suggested the presence non-bridging oxygen (NBO) and BO3 groups that facilitated rapid ion exchange. While bands at 550–650 cm−1 (PO43−) and 1524 cm−1 (CO32−) confirmed the formation of carbonated HA. The porous architecture of bioactive glass facilitated rapid in-vitro mineralization while crystalline bioactive glass improved dimensional stability and controlled degradation which renders it ideal for hard tissue engineering scaffolds where structural integrity is important besides biological functions.
Institutions: Manipal University Jaipur, Lawrence Technological University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,557
OpenAlex ID: W7166103216