Inhibition of ADSS2-mediated de novo AMP biosynthesis re-sensitizes acute myeloid leukemia to BH3 mimetics
Year: 2026
Type: article
Source: Nature Cancer
Authors: Xin He, Lei Zhang, Yang Li, Song-Bai Liu, Zheng Li, Haojie Dong, Genevieve E. Baker, Le Xuan Truong Nguyen, Wei Chen, Jinhui Wang, Zhilian Jia, Xiyuan Lu, Yi-Chun Lin, Zunsong Hu, Umesh Prasad Yadav, Meng Liu, Lianjun Zhang, Zhenhua Chen, Xiwei Wu, Jianjun Chen, Chun-Wei Chen, Stefano Tiziani, Weidong Hu, Ya-Huei Kuo, Sheng-Li Xue, Yong Zhang, Min Li, Yaoqiu Zhu, Guido Marcucci, Zhaohui Gu, J. Jefferson P. Perry, Yun Lyna Luo, Ling Li
Institutions: City Of Hope National Medical Center, City of Hope, Beckman Research Institute, Fujian Medical University, Union Hospital, Suzhou Vocational Health College, Soochow University, First Affiliated Hospital of Soochow University, The University of Texas at Austin, Western University of Health Sciences, University of Southern California
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
Funder: National Cancer Institute
OpenAlex ID: W7166125777