Work

Renal Mucosa-Associated Lymphoid Tissue Lymphoma Mimicking Autoimmune Pancreatitis: A Diagnostic Challenge

Year: 2026

Type: article

Abstract: An 87-year-old man presented with progressive steatorrhea, weight loss, and subsequent hyperglycemic crisis. Initial workup revealed combined exocrine and endocrine pancreatic insufficiency with mildly elevated immunoglobulin G4 below the diagnostic threshold and diffuse pancreatic inflammation on magnetic resonance imaging, raising suspicion for autoimmune pancreatitis. Follow-up imaging revealed an incidental renal mass, which biopsy confirmed as mucosa-associated lymphoid tissue lymphoma. Positron emission tomography-computed tomography demonstrated fluorodeoxyglucose uptake in both the renal mass and pancreatic tissue, with concordant treatment response to rituximab in both locations, suggesting lymphomatous pancreatic infiltration.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000002209

Authors: Peter Kim, Ying Gibbens, Daniela Guerrero Vinsard

Institutions: University of Minnesota, Minneapolis VA Health Care System, Minneapolis VA Medical Center

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7166191365

FWCI:

Cites: 18

Cited by:

Related to: