Warthin-Like Variant of Papillary Thyroid Carcinoma: A Rare Case in an Adolescent Female with Diagnostic and Clinical Insights
Year: 2026
Type: article
Study design: Case Report
Abstract: The Warthin-like subtype of papillary thyroid carcinoma (WL-PTC) represents a rare morphological variant, often linked with Hashimoto’s thyroiditis. Characterized by oncocytic epithelial cells forming papillae amid dense lymphoplasmacytic infiltration, this variant typically presents in adult women. Due to imaging and cytological overlaps with classical PTC, preoperative diagnosis can be intricate. This report details an exceptional case involving an 18-year-old female with a left thyroid lobe nodule. Cytological assessment indicated PTC, later confirmed as WL-PTC following histological evaluation post-thyroidectomy. The tumor exhibited defining oncocytic and nuclear features amid prominent lymphoid stroma. Recognizing such rare variants is crucial to avoid misdiagnosis and to tailor appropriate management, especially given their generally favorable prognosis.
Authors: Kriti Roy, Tanvi Jha, Neha A. Singh
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7166337501