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Characterizing the Reactive Metabolites of Colony-Stimulating Factor 1 Receptor Inhibitor PLX5622 in Liver Microsomes and Mice

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Year: 2026
Type: article
Source: Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.6c00282
Authors: Shenzhi Zhou, Thomas Lee, Xingyu Ji, Kevin R. Mackenzie, Feng Li
Institutions: Baylor College of Medicine, Cornell University
Language: English

Topic: Pharmacogenetics and Drug Metabolism
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development
Award: Elucidating Chemical Features that Block or Facilitate Passage across the Blood-Testis and/or Blood-Epidydimal Barriers in Mice
OpenAlex ID: W7166347650
FWCI:
Cites: 28
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