Work

Solid Dispersion Technology in Tablet Formulation: Principles, Preparation Methods, and Pharmaceutical Applications

Year: 2026

Type: article

Abstract: Poor aqueous solubility limits the oral bioavailability of many active pharmaceutical ingredients (APIs). Solid dispersion technology has emerged as one of the most successful formulation strategies to improve dissolution rate and oral absorption of poorly water-soluble drugs. In tablet formulations, solid dispersions combine enhanced drug release with the convenience, stability, and patient acceptance of oral solid dosage forms. This manuscript reviews the principles, classification, carriers, preparation methods, characterization techniques, tablet formulation strategies, pharmaceutical applications, commercial products, challenges, and future prospects of solid dispersion technology.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.21034633

Authors: Soni Bansod, Prof. Vinayak Munde

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7166515283

FWCI:

Cites:

Cited by:

Related to: