Evaluation of Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy (hipec) in the Multimodal Management of Advanced Peritoneal Carcinomatosis
Year: 2026
Type: article
Study design: Observational Study
Abstract: . This study analyzes the therapeutic efficacy, survival rates, and complication profiles of CRS plus HIPEC in patients suffering from diffuse peritoneal surface malignancies. A retrospective evaluation of patients undergoing this multimodal strategy demonstrated that a low Peritoneal Cancer Index (PCI) and complete cytoreduction (CC-0) are crucial indicators of prolonged overall survival. Despite considerable hematological and gastrointestinal toxicities, the regional dose intensification and thermal enhancement of cytotoxicity offer a substantial survival advantage compared to conventional systemic chemotherapy alone. Keywords: patient, complication, survival, peritoneal cavity, neoplasm, peritoneal cancer, multimodal strategy
Author: Sulaymanov D.A. - PhD
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7166517430
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