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A window of opportunity: tear cytokine profiles in chronic ocular graft-versus-host disease

Year: 2026

Type: article

Abstract: Chronic ocular graft-versus-host disease (GvHD) complicates allogeneic stem cell transplantation, with immune-mediated inflammation and fibrosis of the ocular surface leading to severe dry eye disease (DED). While previous studies have demonstrated elevated tear cytokines in chronic ocular GvHD, few have characterised early-stage cytokine correlations with clinical severity [ 1 , 2 , 3 ].

Source: Eye

DOI: 10.1038/s41433-026-04674-z