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The Role of p-VEGFR2/p-AKT and HDAC1 in Apatinib-associated Inhibition of Gallbladder Cancer Cell Growth

Year: 2026

Type: article

Abstract: Apatinib has been shown to be efficacious in the treatment of gallbladder cancer. However, the underlying mechanisms remain unclear. This study aimed to explore pathways related to the antitumor effects of apatinib at the cellular level in gallbladder cancer.

Source: Exploratory Research and Hypothesis in Medicine

DOI: 10.14218/erhm.2025.00077

Authors: Wei Huang, Yanmin Pang, Wenmei Zhao, Liang’e Xia, Luting Wang, Yingde Nong, Kai Xiao, Yichong Ning

Institutions: Youjiang Medical College for Nationalities, Affiliated Hospital of Youjiang Medical University for Nationalities, Central South University, Second Xiangya Hospital of Central South University

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Hunan Normal University, Natural Science Foundation of Hunan Province

OpenAlex ID: W7166557451

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Cites: 24

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