GREEN SYNTHESIS, CHARACTERIZATION AND ANTI- BACTERIAL ACTIVITIES OF COBALT DOPED ZINC OXIDE NANO COMPOSITE USING Croton macrostachyus LEAF EXTRACT
Year: 2026
Type: dissertation
Abstract: ABSTRACT Microorganism infections have gained significant attention due to the serious health hazards they pose. Because of the concerning increase in outbreaks of pathogenic strains, antibiotic resistance, new bacterial mutations, and other problems, there is an urgent need for effective antimicrobials. Numerous nanoparticles made from metals have been shown to be compatible with human cells and to function as micronutrients crucial to the body's fundamental functions. Many bacterial species, both Gram-positive bacteria and -negative bacteria, are very resilient to the damaging effects of inorganic substances. This study investigated to green synthesis, characterization and antibacterial activity of cobalt doped zinc oxide nanocomposite using Croton macrostachyus leaf extract. The synthesized nanoparticles were characterized by using UV-Vis, FTIR and XRD spectroscopic and tested antibacterial activities. The UV-Visible spectra showed absorbance peaks at 268 nm, 358 nm and 366 nm for Croton macrostachyus leaf extract, ZnONPs and Co-ZnO NCs respectively. The band gap energy, calculated was 3.06 eV and 2.6 eV for ZnO NPs and Co/ZnO NCs respectively. FTIR confirmed the nature of bonds and functional groups in the leaf extract, ZnO and Co-ZnO NCs. The XRD analysis reveals all the synthesized particles have a crystalline with average particle sizes of 10.16 nm,7.19nm and 9.22nm of ZnONPs, 5%Co/ZnONCs, 7%Co/ZnO NCs respectively. The bacterial activity of studies of the synthesize 5% Co-ZnO NCs ,7%Co-ZnO NCs against S,aures, E,coli and p.aeruginosa showed good potential with the reference to the selected standards ciprofloxacin The maximum zone of inhibition activities were found against gram negative(p.areuginosa) for 7% Co-ZnO NCs followed by 5% Co-ZnO NCs whereas minimum inhibition zone were against gram negative (E.coli) for ZnO NPs.And also the determination of the size and composition of the sample is characterized using instruments like SEM,TEM,XPS and EDX. Keywords: Antibacterial ,Characterization ,Croton macrostachyus ,Green synthesis, , Nanocomposites,
DOI: 10.20372/nadre:25534
Author: TEFERI GEBISA NEGERI
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7166561470