Work

Congenital soft tissue sarcoma of the neck with placental metastasis: a case report

Year: 2026

Type: article

Abstract: Congenital round cell soft tissue sarcoma with metastasis to the placenta is rarely described. We report a case of a large soft tissue sarcoma of the left neck from a female fetus delivered at 36 weeks and 3 days with metastasis to the stem villous vessels of the placenta. The tumor showed mixed features of Ewing sarcoma/primitive neuroectodermal tumor (PNET) and infantile fibrosarcoma with ETV6 :: NTRK3 fusion gene transcript. The clinical significance and diagnostic pitfalls are discussed.

Source: Surgical and Experimental Pathology

DOI: 10.1186/s42047-026-00250-7

Authors: Michelle Nguyen, Jennifer Ahn, Art Mendoza, Chris Wixom, Omid Bakhtar, Peilin Zhang

Institution: Sharp Memorial Hospital

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7166564501