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Reprogramming ThDP Enzymes for Z -Alkenes: Overriding Thermodynamic Preference via Noncovalent Controls

Year: 2026

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.6c06951

Authors: Huangong Li, Tairan Yang, Yilong Zhao, Rui Pan, Jinmin Peng, Yinhong Lai, Jingyu Zhang, Xueting Liu, Guoliang Zhu, Lixin Zhang, Yonggui Robin Chi, Yongtao Xie

Institutions: East China University of Science and Technology, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Nanyang Technological University, Guizhou University

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, State Key Laboratory of Bioreactor Engineering, Higher Education Discipline Innovation Project, International Cooperation and Exchange Programme

Awards: G3010699597, G3121624668, G4024509393, G4155290071, G4642909846, G525636489, G5621967601, G8876056543

OpenAlex ID: W7166567413

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Cites: 42

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