Association of Sleep Duration Ratio with a Reduced Risk of Heart Failure: Analysis of the 2017–2023 National Health and Nutrition Examination Survey
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background/Objectives: In the United States, HF prevalence is projected to progressively rise by 2030. Prior research suggests a strong association between reduced sleep duration and increased cardiovascular disease and HF risk. This study introduces an alternative parameter, the weekend sleep recovery (WSR), measured by the weekend-to-weekday sleep duration ratio (SDR), to evaluate its association with HF risk. Methods: We conducted a cross-sectional analysis of NHANES (National Health and Nutrition Examination Survey) 2017–2023 to examine self-reported sleep patterns. Participants were classified as WSR (SDR > 1) or non-WSR (SDR ≤ 1). Multivariate logistic regression assessed the association between WSR and HF, adjusting for demographics and comorbidities. Results: Among 8320 participants included in the fully adjusted analysis, WSR was associated with lower odds of HF compared with non-WSR (adjusted OR 0.73, 95% CI 0.55–0.96; p = 0.026). A significant interaction was observed between WSR and weekday sleep duration (P for interaction = 0.003), whereas no interaction was found with weekend sleep duration. In exploratory subgroup analyses, nominally significant associations were observed in several clinical subgroups; however, after correction for multiple comparisons, only participants without dyslipidemia retained statistical significance. No significant effect modification by race/ethnicity was observed (P for interaction = 0.436). Conclusions: Weekend sleep recovery was associated with lower odds of HF in this cross-sectional study. The association varied according to weekday sleep duration but was generally consistent across racial/ethnic groups. Given the observational design, these findings should be interpreted as associative rather than causal and warrant confirmation in prospective studies.
Source: Journal of Clinical Medicine
DOI: 10.3390/jcm15135047
Authors: Narathorn Kulthamrongsri, Thanathip Suenghataiporn, Adivitch Sripusanapan, Smuch Siramongkholkarn, Thitiphan Srikulmontri, Chanokporn Puchongmart, Thanaboon Yinadsawaphan, Ben Thiravetyan, Kridhitach Ngarmukos, Koravich Lorlowhakarn, Nathasith Tangprasittichok, Ekamol Tantisattamo, Abdulelah Nuqali
Institutions: University of Hawaiʻi at Mānoa, Mayo Clinic, University of Hawaii System, University of California, Irvine, University of California, Irvine Medical Center, Mayo Clinic Hospital, Griffin Hospital, Boston Medical Center, Jefferson Einstein Philadelphia Hospital, Texas Tech University, Texas Tech University Health Sciences Center, Mahidol University, Phramongkutklao College of Medicine, Queen's Medical Center, Oakland University, Pacific Northwest University of Health Sciences, Beaumont Health, Beaumont Hospital, Royal Oak, Ramathibodi Hospital, Corewell Health William Beaumont University Hospital
Language: English
Topic: Sleep and related disorders
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W7166576661