Work

Wheat’s Up with CRISPR-Cas—Current Advances, Obstacles and Perspectives

Year: 2026

Type: article

Abstract: The emergence of CRISPR-Cas editing systems—comprising clustered regularly interspaced short palindromic repeats and associated Cas proteins—marked a breakthrough in genetic engineering, owing to the simplicity, efficiency, and adaptability of the method. Despite continuous improvements and the incorporation of innovative discoveries to develop reliable, fine-tuned tools, the effective application of CRISPR-Cas technology in cereals remains challenging. This review provides a technically oriented overview of CRISPR-Cas-mediated genome editing in wheat (Triticum aestivum L.), one of the world’s fundamental crops. While focusing on established solutions and progressive methodological modifications, we also discuss pertinent topics, including plant genetic transformation, prospective innovations, and compliance considerations.

Source: International Journal of Molecular Sciences

DOI: 10.3390/ijms27135860

Authors: Monika Samoń, Mateusz Przyborowski

Institution: Plant Breeding and Acclimatization Institute - National Research Institute

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $3,499