Type 1 autoimmune pancreatitis presenting with obstructive jaundice and mimicking pancreatic cancer: a case report
Year: 2026
Type: article
Study design: Case Report
Abstract: Type 1 autoimmune pancreatitis is a fibroinflammatory condition within the immunoglobulin G4 (IgG4)-related disease spectrum, characterized by lymphoplasmacytic infiltration, storiform fibrosis, and elevated serum IgG4 levels.It represents a significant diagnostic challenge due to its frequent radiologic and clinical overlap with pancreaticobiliary malignancies.We describe the case of a 70-year-old male who developed obstructive cholestasis after endoscopic treatment for choledocholithiasis.Multimodal imaging, including endoscopic retrograde cholangiopancreatography, magnetic resonance cholangiopancreatography, and positron emission tomography-computed tomography, showed biliary strictures, a pancreatic head mass, and metabolically active lymphadenopathy.Histopathologic confirmation through endoscopic ultrasound-guided biopsy, along with serologic results, established the diagnosis.Early corticosteroid therapy resulted in significant biochemical and radiologic improvement.
Source: Endoscopia
Authors: Iván López-Méndez, Claudia Maya-Salazar
Institution: Hospital Médica Sur
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7166587793
FWCI:
Cites:
Cited by:
Related to: