Work

Acute myocardial interstitial edema from pathophysiology to therapeutic considerations in critical care: a narrative review

Year: 2026

Type: review

Abstract: The excess accumulation of fluid in the extracellular space of the heart determines a condition of “myocardial interstitial edema.” Myocardial edema is present in multiple pathological conditions observed in the intensive care setting: fulminant myocarditis, sepsis-induced cardiomyopathy, cardiac arrest, capillary leak syndrome, and extracorporeal circulation. Fluid accumulation in the interstitium can occur rapidly, leading to severe heart failure and potentially progressing to cardiogenic shock. Early diagnosis and prompt therapy are crucial. Understanding the factors and diseases that can disrupt myocardial fluid homeostasis and contribute to the development of interstitial edema allows for a targeted therapeutic approach, aimed at reducing fluid accumulation and clinical detrimental effects.

Source: Emergency and Critical Care Medicine

DOI: 10.1097/ec9.0000000000000198

Authors: Alessandra Volontè, Emanuele Catena

Institutions: Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Luigi Sacco Hospital

Language: English

Topic: Takotsubo Cardiomyopathy and Associated Phenomena

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7166641835

FWCI:

Cites: 33

Cited by:

Related to: