Year: 2026
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide A laboratory experiment was developed for the preparation of a thin-layer chromatography stain from the condensation of furfural and N -methylbarbituric acid. The experiment allows for the introduction of the concepts of selective TLC staining and colorimetric detection of amines. The stain is based on the formation of donor–acceptor-Stenhouse-adducts (DASAs), and its preparation and application allow the introduction of organic chemistry concepts such as the Knoevenagel condensation, ring opening, and Nazarov electrocyclization, as well as photochromic systems. The cheap reagents required for this work and easy setup allow for a straightforward introduction of the work in various settings, including academic laboratories. The use of biomass-derived furfural reinforces the importance of green chemistry and sustainable practices in organic chemistry.
Source: Journal of Chemical Education
Institution: University of Lisbon
Language: English
Subfield: Physical and Theoretical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
Awards: Instituto de Investigação do Medicamento, G1297482482, Redução Fotoquímica de Proteínas, G1578237752, Expansão do espaço químico da quitina através da ativação C-H seletiva, G2588286954, Ultra-Alta Pressão como uma ferramenta sustentável para quimo-selectividade ajustável, G3891694003, G3962548093, G5834163289, G6232535371, G6501507638, Straightening training, research and innovation capacities in the valorization of bio-renewable resource, G8954508221
OpenAlex ID: W7166655159