Additional file 1 of Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein
Year: 2013
Type: other
Abstract: Additional file 1: Figure S1: Lack of induction of αS pathology throughout the neuroaxis 8 months after neonatal brain injection of 25 μg Δ71-82 αS in M20 Tg mice. Tissue sections were stained with pSer129. Brain regions that typically showed Lewy body/neurite-like pathology after injection of 25 μg Δ71-82 αS in M20 Tg mice, were blank in an unaffected mouse: the medial preoptic area (MPA), striatum (ST), thalamus (TH), hypothalamus (HYP), substantia nigra (SN), ventral pons (VP), entorhinal cortex (EC), amygdala (AMY), and CA3 region of the hippocampus (CA3). Tissue sections were counterstained with hematoxylin. Scale bars = 100 μm (MPA), 50 μm (EC), 100 μm (ST), 100 μm (AMY), 200 μm (CA3), 50 μm (TH), 100 μm (HYP), 50 μm (SN), and 100 μm (VP). (TIFF 813 KB)
Source: Figshare
Institution: University of Florida
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7166711561
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