Understanding Hyperthyroidism: Etiologies, Mechanisms, and the Role of Percutaneous Thermal Ablation
Year: 2026
Type: article
Abstract: Hyperthyroidism comprises a spectrum of disorders ranging from overt, symptomatic disease to subclinical disease and affects multiple organ systems. This review summarizes key causes, diagnostic strategies, and treatment approaches in adults, focusing on Graves' disease, autonomous functioning thyroid nodules (AFTNs), toxic multinodular goiter, and thyroiditis. The article focuses on the role of percutaneous image-guided ablation for selected patients with solitary AFTNs as a treatment modality for patients. Current evidence demonstrates high rates of biochemical remission, marked volume reduction, low complication rates, and durable outcomes, positioning ablation as an increasingly attractive option in modern hyperthyroidism management.
DOI: 10.1055/a-2859-5063
Authors: Olga S. Senashova, James Y. Lim
Institution: Oregon Health & Science University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7166728706