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Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02812
Authors: Yunlong Lu, Lijuan Liu, Zhenlin Liang, Wayne A Schroder, Zhenfan Wen, Tianpeng Zheng, Ben Niu, Chunqi Xie, He Zhang, Jian Min, Qianming Du, Wukun Liu
Institutions: Nanjing University of Chinese Medicine, Griffith University, China Pharmaceutical University, Nanjing First Hospital, Hubei University
Language: English

Topic: Estrogen and related hormone effects
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Jiangsu Commission of Health, National Natural Science Foundation of China, Nanjing University of Chinese Medicine, Jiangsu Provincial Key Research and Development Program
Awards: G1678611135, G2439684311, G2671298683, G4582863646, G6301065862
OpenAlex ID: W7166733342
FWCI:
Cites: 48
Cited by:
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