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Oncological Safety of Minimally Invasive Multivisceral Resection for cT4b Rectal Cancer: A Multicenter Comparison With Open Surgery

Year: 2026

Type: article

Abstract: BACKGROUND/AIM: Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, is increasingly used for rectal cancer but evidence of multivisceral resection (MVR) for cT4b disease by MIS is limited. This study compared short- and long-term outcomes between patients who underwent MIS or open MVR for advanced rectal cancer. PATIENTS AND METHODS: We retrospectively analyzed 32 patients with cT4b rectal cancer who underwent rectal resection with MVR at six institutions between 2011 and 2023 (open, n=9; MIS, n=23). Operative invasiveness, postoperative complications, and 3-year survival were evaluated. RESULTS: <0.0001). After excluding those with stage IV disease (open, n=9; MIS, n=20), pathological outcomes and 3-year survival did not differ between groups. CONCLUSION: MIS may reduce invasiveness without compromising oncological outcomes in selected patients with cT4b rectal cancer requiring MVR.

Source: In Vivo

DOI: 10.21873/invivo.14375

Authors: SHO NAMBARA, KOJI ANDO, TOMOYA HARIMA, SHINICHIRO IKEDA, TETSURO KAWAZOE, HIROFUMI HASUDA, KENTARO NONAKA, YUTA KASAGI, YASUO TSUDA, YOSHIHIKO FUJINAKA, TOMONORI NAKANOKO, RYOTA NAKANISHI, MASAHIKO SUGIYAMA, DAISUKE YOSHIDA, KIPPEI OHGAKI, EIJI OKI, TOMOHARU YOSHIZUMI

Institutions: Kyushu University, National Kyushu Medical Center, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, National Hospital Organization Kyushu Cancer Center, Aso Iizuka Hospital, Beppu Medical Center, Kyushu University Hospital

Language: English

Topic: Colorectal Cancer Surgical Treatments

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7166765394

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