Work

Incremental Prognostic Value of the Haemoglobin-Albumin-Lymphocyte-Platelet Score and B-Type Natriuretic Peptide for 30-Day Mortality After Elective On-Pump Coronary Artery Bypass Grafting

Year: 2026

Type: article

Abstract: OBJECTIVES: This study evaluated whether preoperative haemoglobin-albumin-lymphocyte-platelet (HALP) score and B-type natriuretic peptide (BNP) were associated with 30-day mortality after elective on-pump coronary artery bypass grafting (CABG) and whether they improved prognostic assessment beyond European System for Cardiac Operative Risk Evaluation II (EuroSCORE II). METHODS: Among 492 eligible patients, 466 with complete data on 30-day mortality and the prespecified primary predictors constituted the primary analytic cohort. Associations were examined using Firth penalized logistic regression, and internal validation was performed with bootstrap resampling. RESULTS: Twenty-one patients (4.5%) died within 30 days. Lower HALP and higher BNP were independently associated with mortality after adjustment for EuroSCORE II. The optimism-corrected area under the curve improved from 0.879 for EuroSCORE II alone to 0.974 after the addition of HALP and to 0.979 after further addition of BNP. CONCLUSIONS: Lower HALP and higher BNP were associated with 30-day mortality after elective on-pump CABG and may provide incremental prognostic information beyond EuroSCORE II. These findings should be considered exploratory.

Source: Interdisciplinary CardioVascular and Thoracic Surgery

DOI: 10.1093/icvts/ivag190

Authors: Hafize Yalınız, Onur Benli

Institution: Cukurova University

Language: English

Topic: Cardiac and Coronary Surgery Techniques

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,258