Supplementary Figure S5 from Development of a Clinical Assay to Guide Patient Therapy in HPV-Associated Head and Neck Cancer
Year: 2026
Type: supplementary-materials
Abstract: Supplemental Figure 5. NF-κB pathway mutations are found in cases with high NF-κB scores. A) NanoString NF-κB expression scores and NF-κB pathway mutational data from UNC cohort where both metrics were available. B) Non-linear least squares fit of mono-exponential function relating NanoString and RNAseq data. This fit was used to transpose the threshold defined by NanoString to the RNAseq data, where 3 more cases were available.
Authors: Sri Vemulamanda, Aditi Kothari, Loris De Cecco, Sulgi Kim, Aditi Kulkarni, Pragati Upadhyay, Stefano Cavalieri, Christophe Courtine, Yasine Mirmozaffari, Jane Brown, Andrew Sewell, Yael Flamand, Yue Xie, Lili Zheng, Shanthi Marur, Trevor Hackman, Bart Singer, John Ayman Hakim, Lori Ramkissoon, Yan Li, Hina Rehmani, Xue Li, Siddharth Sheth, Xuguang Chen, Jennifer Dorth, Quintin Pan, Evan Graboyes, Bhishamjit Chera, Barbara Burtness, Robert L. Ferris, Rene Leemans, Ruud H. Brakenhoff, Frank Hoebers, Kathrin Scheckenbach, Tito Poli, Lisa Licitra, Wendell G. Yarbrough, Natalia Issaeva, Travis P. Schrank
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7166817310