Year: 2026
Type: conference-paper
Abstract: Large language models (LLMs) are increasingly explored for patient-facing medical advice and symptom triage, yet their responses may shift when identical clinical evidence is paired with culturally marked patient descriptors.We present a counterfactual audit framework for evaluating cross-cultural variation in LLM-generated medical advice by isolating identity-related cues while holding clinical evidence constant.Our evaluation uses matched clinical vignettes, cross-regional and culturally marked prompt variants, repeated sampling, and structured comparison of urgency framing, safety recommendations, empathy, and escalation advice.Across multiple commercial and open-weight LLMs, we observe measurable identity-conditioned variation in both triage decisions and interactional framing.In several cases, culturally marked descriptors shift urgency assessments or escalation recommendations despite unchanged clinical evidence.While the magnitude and direction of these effects differ across models, the results suggest that LLM-generated medical advice remains sensitive to culturally linked identity cues in ways that may affect safety-critical guidance.Our results demonstrate how culturally grounded counterfactual auditing can help identify clinically unsupported variation while distinguishing potentially harmful shifts from appropriate communication adaptation in patient-facing medical advice.
Authors: Hyunwoo Yoo, Gail Rosen
Institution: Drexel University
Language: English
Subfield: Health Informatics
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7166869968
