Supplementary Figure S7 from Development of a Clinical Assay to Guide Patient Therapy in HPV-Associated Head and Neck Cancer
Year: 2026
Type: supplementary-materials
Abstract: Supplemental Figure 7. IF staining was performed at UNC Pathology Services Core. Patients in the UNC RNAseq cohort were stratified by RNA NF-κB Signature score as previously published. (1) The following antibodies were used: NIK antibody: Cat#SC-8417 (Santa Cruz) and Pan CK: Leica NCL-L-AE1/AE3-601 (Leica). High resolution images of IF slides were obtained performed with the Aperio Versa 200 scanner (Leica Biosystems Inc.) at an apparent magnification of 10X. Images were uploaded to the eSlideManager database (Aperio) at the Pathology Services Core at UNC. ** p-value <0.00005, Wilcox test.
Authors: Sri Vemulamanda, Aditi Kothari, Loris De Cecco, Sulgi Kim, Aditi Kulkarni, Pragati Upadhyay, Stefano Cavalieri, Christophe Courtine, Yasine Mirmozaffari, Jane Brown, Andrew Sewell, Yael Flamand, Yue Xie, Lili Zheng, Shanthi Marur, Trevor Hackman, Bart Singer, John Ayman Hakim, Lori Ramkissoon, Yan Li, Hina Rehmani, Xue Li, Siddharth Sheth, Xuguang Chen, Jennifer Dorth, Quintin Pan, Evan Graboyes, Bhishamjit Chera, Barbara Burtness, Robert L. Ferris, Rene Leemans, Ruud H. Brakenhoff, Frank Hoebers, Kathrin Scheckenbach, Tito Poli, Lisa Licitra, Wendell G. Yarbrough, Natalia Issaeva, Travis P. Schrank
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7166886547