Work

Supplementary Figure S7 from Adaptive Regulation of dNTP Homeostasis Confers Osimertinib Resistance in EGFR-Mutant Non–Small Cell Lung Carcinoma

Year: 2026

Type: supplementary-materials

Abstract: Prolonged RRM2B knockdown increases mitochondrial DNA levels. RRM2B knockdown does not affect sensitivity to Osimertinib, and RRM2 knockdown does not affect RRM2B protein levels.

DOI: 10.1158/0008-5472.32873069

Authors: Qian Xie, Yingying Wang, Anthony Fernandez, Yi Lei, Yuanhang Gong, Jessica D. Hess, Lin Yang, Di Xin, Terence M. Williams, Li Zheng, Binghui Shen, Min Li

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7167023767

Cites:

Cited by:

Related to: