Work

Cytokine profiles in patients with chronic kidney disease and low sexual function

Year: 2026

Type: article

Abstract: This study is the first to investigate cytokine profiles in women with advanced CKD and low sexual function. We found that lower levels of soluble CD40 ligand were independently linked to higher odds of having low sexual function. Principal component analysis demonstrated that a broader immune activation pattern was associated with higher odds of having low sexual function. Together, these findings suggest that immune signaling patterns may be relevant to sexual health in women with CKD.

Source: American Journal of Physiology-Renal Physiology

DOI: 10.1152/ajprenal.00081.2026

Authors: Jose Arriola-Montenegro, Sonja Suvakov, Angie S. Lobo, Melissa Felt, Vesna D. Garovic, Andrea G. Kattah

Institutions: Mayo Clinic, University of Minnesota

Language: English

Topic: Sexual function and dysfunction studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases