Supplemental Figure 1. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young
Year: 2026
Type: supplementary-materials
Abstract: Study schematic. Created in BioRender. Fleuren, E. (2026) https://BioRender.com/605mjau. Abbreviations: CNV: copy number variation, EWS: Ewing sarcoma, FP-RMS: fusion-positive rhabdomyosarcoma, FN-RMS: fusion-negative rhabdomyosarcoma, HGU: high-grade undifferentiated sarcoma, MTB: Multidisciplinary Tumor Board, OS: osteosarcoma, PDX: patient-derived xenograft, ptn: patient, pY: tyrosine phosphorylation, SNV: single nucleotide variant, SV: structural variant, TK: tyrosine kinase, TPM: transcripts per kilobase million, ZERO: ZERO Childhood Cancer precision medicine program.
Authors: Ashleigh M. Fordham, Lauren M. Brown, Chelsea Mayoh, Alice Salib, Zara A. Barger, Marie Wong, Terry C.C. Lim Kam Sian, Changyuan Hu, Jinhan Xie, Kate Gunther, Peter Trebilcock, Rachael L. Terry, Paulette Barahona, Pamela Ajuyah, Alexandra Sherstyuk, Anica Avila, Roxanne Cadiz, Callum M. Perkins, Andrew J. Gifford, Jie Mao, M. Emmy M. Dolman, Andrea Zhao, Luke P. O’Regan, Daniel Gorgels, Loretta M.S. Lau, David S. Ziegler, Michelle Haber, Vanessa Tyrrell, Richard B. Lock, Mark J. Cowley, Wayne Nicholls, Roger J. Daly, Paul G. Ekert, Emmy D.G. Fleuren
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7167037389