Supplemental Figure 6. from Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young
Year: 2026
Type: supplementary-materials
Abstract: A) Heatmap visualizing RNA TPM counts of the FGFR-pathway across the sarcoma cell line panel, ordered based on histology and FGFR genes. B) Public gene expression data of FGFR4 RNA (left panel) and FGF8 RNA (right panel) was extracted and visualized for sarcoma cell lines from DepMap (n=137 sarcoma (11 FP- RMS, 13 FN-RMS; DepMap.org)). C) Correlation between FGFR4 and FGF8 RNA expression across sarcoma cell lines.
Authors: Ashleigh M. Fordham, Lauren M. Brown, Chelsea Mayoh, Alice Salib, Zara A. Barger, Marie Wong, Terry C.C. Lim Kam Sian, Changyuan Hu, Jinhan Xie, Kate Gunther, Peter Trebilcock, Rachael L. Terry, Paulette Barahona, Pamela Ajuyah, Alexandra Sherstyuk, Anica Avila, Roxanne Cadiz, Callum M. Perkins, Andrew J. Gifford, Jie Mao, M. Emmy M. Dolman, Andrea Zhao, Luke P. O’Regan, Daniel Gorgels, Loretta M.S. Lau, David S. Ziegler, Michelle Haber, Vanessa Tyrrell, Richard B. Lock, Mark J. Cowley, Wayne Nicholls, Roger J. Daly, Paul G. Ekert, Emmy D.G. Fleuren
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7167061515