Work

Systemic, RPE-directed AAV- Tyrosinase therapy restores ocular pigmentation in an OCA1 mouse model

Year: 2026

Type: preprint

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.64898/2026.07.01.735814

Authors: Alessandra M. Larimer-Picciani, Lucas B. Jacob, Kacey J. Sullinger, Wyatt G. Kriebel, José-Alain Sahel, Leah C. Byrne

Institutions: University of Pittsburgh, Centre National de la Recherche Scientifique, Institut de la Vision, Inserm, Sorbonne Université

Language: English

Topic: Retinal Development and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Research to Prevent Blindness

OpenAlex ID: W7167113700

Cites: 48

Cited by: 1

Related to: 10