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Targeting SYK to alleviate MDSC-driven immunosuppression and augment anti-PD1 efficacy

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Year: 2026
Type: article
Source: Science China Life Sciences
DOI: 10.1007/s11427-025-3230-6
Authors: Zhiyang Zeng, Xiya Cao, Changwei Li, Youyuan He, Haozhe Guo, Xiaoya Cao, Tingyue Gong, Jialiang Sun, Yaqiang Hu, Zhongwei Hu, Yuxuan Lai, Dan Zhang, Neil Warner, Holm H. Uhlig, Qi Li, Aleixo M. Muise, Yamin Tan, Ying Huang, Lianfu Deng, Liufu Deng, Zhenliang Sun, Ming Zhong, Xueli Zhang, Dali Li
Institutions: Southern Medical University, East China Normal University, Shanghai Jiao Tong University, Ruijin Hospital, Renji Hospital, Hospital for Sick Children, Sickkids Research Institute, John Radcliffe Hospital, University of Oxford, University of Toronto, Chinese Academy of Sciences, Zhejiang Cancer Hospital, University of Chinese Academy of Sciences, Fudan University, Children's Hospital of Fudan University, Shanghai Institute of Immunology
Language: English

Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7167361448
FWCI:
Cites: 80
Cited by:
Related to: 10
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