Dataset for Cytochrome P450 Expression Influences Behavioral Responses to Gestational and Lactational Exposure to Polychlorinated Biphenyl (PCB) 11 in Juvenile Male and Female Mice
Year: 2026
Type: dataset
Abstract: As part of a larger study on neurodevelopmental effects of lower‑chlorinated PCB 11, we quantified PCB 11 and metabolites in postnatal day (P)21 and P35 mouse pup serum exposed orally to PCB 11 via the maternal diet. We used gas chromatography mass spectrometry-tandem mass spectrometry (GC‑MS/MS) to quantify PCB 11 and liquid chromatography-high resolution mass spectrometry (LC-HRMS) to screen for additional PCB 11 metabolites. The accompanying dataset contains raw and processed files from the GC-MS/MS and LC-HRMS, including PCB 11 and associated metabolite concentrations, detection limits, recoveries, and chromatogram peak areas.
DOI: 10.25820/data.008279
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: green
Awards: PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?, Molecular and Cellular Basis of PCB Developmental Neurotoxicity, Advanced Training in Environmental Health Sciences, Initiative for Maximizing Student Development at the University of California, Davis.
OpenAlex ID: W7167744681