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Solitary myofibroma of the oral cavity; a rare case report

Year: 2026

Type: article

Abstract: Myofibroma is an uncommon benign neoplasm of myofibroblastic origin that primarily affects children and adolescents. While it most frequently arises in the skin and subcutaneous tissues, its occurrence in the oral cavity, particularly in the buccal soft tissue is exceptionally rare. Owing to its clinical similarity to other benign spindle-cell lesions, such as irritation fibroma and neural tumors, establishing an accurate diagnosis can be challenging. This report describes a rare case of solitary oral myofibroma presenting as a buccal soft tissue swelling of the left mandible. The clinical, radiographic, histopathologic, and immunohistochemical features are presented, together with a discussion on differential diagnosis, management, and prognosis.

Source: Journal of Preventive Epidemiology

DOI: 10.34172/jpe.39314

Authors: Saman Abbasi, Parto Nasri, Maryam Mohebiniya, Salar Nasr Esfahani, Ehsan Momeni

Institutions: Arak University of Medical Sciences, Isfahan University of Medical Sciences

Language: English

Topic: Oral and Maxillofacial Pathology

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7167803038