Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment
Year: 2025
Type: article
Source: Immunity
Authors: William D. Green, Amber Gomez, Alec L. Plotkin, Brandon M. Pratt, Emily F. Merritt, Genevieve N. Mullins, Nancy P. Kren, Jennifer L. Modliszewski, Vasyl Zhabotynsky, Mark G. Woodcock, Jarred M. Green, Gabrielle Cannon, Matthew E. Pipkin, Gianpietro Dotti, Jessica E. Thaxton, Yuliya Pylayeva-Gupta, Albert S. Baldwin, John P. Morris, Natalie Stanley, J. Justin Milner
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
Funders: Mary Kay Foundation, V Foundation for Cancer Research, Hirshberg Foundation for Pancreatic Cancer Research, American Association of Immunologists, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, University of North Carolina, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: CAROLINA CANCER NANOTECHNOLOGY TRAINING PROGRAM (C-CNTP), Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and function, G3809281974, Molecular Programming of CD8+ T Cell Accumulation and Activity in Tumors, Predoctoral Training Program in Bioinformatics and Computational Biology, Center for Gastrointestinal Biology and Disease, Selective Targeting of Pancreatic Cancer SPORE, Training Program in Cellular Systems and Integrative Physiology, Cancer Center Support Grant
OpenAlex ID: W4410741303