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A Case of Synchronous Subcarinal Lymph Node Metastasis from Double Primary Cancers with Small Cell Lung Cancer and Prostate Cancer

Year: 2026

Type: article

Abstract: A 78-year-old man presented with a history of weight loss. A systemic examination revealed lung and prostate cancers. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of a subcarinal lymph node revealed combined small-cell and non-small-cell carcinoma. Prostate-specific antigen (PSA) staining was performed to exclude distant metastases from prostate cancer. A positive result confirmed synchronous lymph node metastasis from a double cancer of small cell lung cancer and prostate cancer. When biopsies reveal multiple histological types, the possibility of metastasis from other cancer types should be carefully evaluated.

Source: Internal Medicine

DOI: 10.2169/internalmedicine.6883-25

Authors: Tsukasa Satoh, Ryota Saito, Toshio Oyama, Ryosuke Tajiri, Kazuyuki Miyata, Hinata Matsuda, Takuya Inoue, Kouki Hata, Makoto Kawaguchi, Hiroaki Kobayashi, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita

Institutions: Yamanashi Prefectural Central Hospital, Kofu Municipal Hospital

Language: English

Topic: Metastasis and carcinoma case studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7167898846

FWCI:

Cites: 16

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Related to: 10