Work

Bioactive hyaluronic acid hydrogels based on lysine dendrigrafts as crosslinkers: impact of stiffness and viscoelasticity on the osteogenic differentiation of mesenchymal stem cells

Year: 2026

Type: article

Abstract: Hydrogels of hyaluronic acid and poly( l -lysine) dendrigrafts bearing bioactive signals induce the osteogenic differentiation of mesenchymal stem cells. The use of dendrigrafts permits to probe the impact of mechanical parameters on differentiation.

Source: Materials Advances

DOI: 10.1039/d6ma00379f

Authors: Evgeny Apartsin, Michele Valeo, Sébastien Marie, Fabien Granier, Marie-Christine Durrieu

Institutions: Centre National de la Recherche Scientifique, Chimie et Biologie des Membranes et des Nanoobjects, Institut Polytechnique de Bordeaux

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,962

Funder: Agence Nationale de la Recherche