Work

Unlocking the potential of Glycosidase-Cleavable AgroDrug Conjugates for Sustainable Agriculture

Year: 2026

Type: preprint

Abstract: The Crop protection industry is currently locked in a race to discover the next generation of efficacious, safe and disruptive modalities. Towards this endeavour, Agrodrug conjugates (AgDCs) offer many unique opportunities to tune the properties of active agrodrugs via meticulous selection of their distinct components. Herein, we present the first study on the utilization of cleavable conjugates for agricultural applications. This proof-of-concept study demonstrates the potential of AgDCs for use in crop protection and establishes this modality as an innovative addition to the toolbox for optimizing bio-active crop protection modalities.

Source: ChemRxiv

DOI: 10.26434/chemrxiv.15005997/v1

Authors: Giulia Cazzaniga, Josephine Mittendorf, Giusy L. Fratello, Marc Linka, Wolfgang Schulte, Jannis Rinne, Orwa Barakat, Alexander T. Apostle, Samuele Bongiolo, Francesco Talarico, Roberto Orru, David M. Barber, Silvia Gazzola

Institutions: University of Insubria, Bayer (Germany)

Language: English

Topic: Polymer-Based Agricultural Enhancements

Subfield: Agronomy and Crop Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: green

OpenAlex ID: W7168144251

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