The Brain-gut-axis in Ayurveda: a Neuro-metabolic Analysis of Krodha Induced Agni-dushti
Year: 2026
Type: article
Abstract: Krodha (anger) is an intense Manas Bhava (mental emotion) explicitly described in Ayurveda as having an Aagneya (fiery) and Ushna (hot) nature.[1,4,7] This inherent feature directly links Krodha with the deranged state of Pitta Dosha and functional derangement of Agni (digestive/metabolic fire), thus establishing a classical psycho-metabolic axis.[4,6] This review gives an integration of classical Ayurvedic concepts and modern psychoneuroimmunology (PNI) to explain the exact mechanism of how acute and chronic Krodha causes a shift in Jatharagni (main digestive fire) from a balanced state (Sama Agni) to a hyperfunctional state (Tikshna Agni), leading to the manifestation of Pitta-dominant disorders such as Amlapitta (hyperacidity/GERD).[9,10] The findings emphasize the need for the integration of Satvavajaya Chikitsa (Ayurvedic psychotherapy) with metabolic correction for the successful management of psychosomatic diseases.
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7168247359
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