Year: 2026
Type: article
Abstract: The review provides a comprehensive overview of lipid and polymeric nanocarriers as advanced delivery systems for the controlled release of nutritional bioactive molecules.Bioactive compounds such as vitamins, polyphenols, carotenoids, and omega-3 fatty acids offer significant health benefits; however, their practical application is often limited by poor solubility, instability, and low bioavailability.Nanocarrier-based systems have emerged as effective solutions to overcome these challenges by enhancing encapsulation efficiency, protecting bioactives from degradation, and enabling controlled and targeted release.Lipid-based nanocarriers, including solid lipid nanoparticles, nanostructured lipid carriers, liposomes, and nanoemulsions, provide excellent biocompatibility and are particularly suitable for lipophilic compounds.In contrast, polymeric nanocarriers offer tunable release kinetics and structural versatility, allowing precise control over delivery profiles.This review further examines key factors influencing controlled release, such as particle size, surface charge, carrier composition, and environmental conditions.Additionally, recent advancements, including stimuliresponsive systems, hybrid nanocarriers, and artificial intelligence-driven formulation design, are discussed.Despite their potential, challenges related to scalability, safety, regulatory approval, and integration into food systems remain.Overall, nanocarrier technologies represent a promising approach for improving the functionality and efficacy of bioactive compounds, paving the way for next-generation functional foods and nutraceuticals.
Language: English
Topic: Proteins in Food Systems
Subfield: Food Science
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W7168387279