Work

Fulminant Lupus Myocarditis Presenting with Cardiogenic Shock and Persistent Complete Atrioventricular Block

Year: 2026

Type: article

Abstract: : Fulminant myocarditis is an uncommon but severe cardiac manifestation of systemic lupus erythematosus (SLE), which can rapidly progress to heart failure and life-threatening rhythm disturbances. We report the case of a 33-year-old woman with a recent diagnosis of SLE who developed rapidly progressive cardiac involvement leading to cardiogenic shock and complete atrioventricular block. Her condition required intensive care management, including mechanical ventilation and temporary pacing. Following treatment with high-dose corticosteroids and cyclophosphamide, a marked improvement in ventricular function was observed, with the left ventricular ejection fraction increasing from 20% to 48%. Despite this recovery, the conduction abnormality persisted. This case highlights the fulminant presentation of lupus myocarditis, the reversibility of myocardial dysfunction and the potential persistence of conduction system involvement.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.21393546

Authors: Ibenchekroun Meryem, Fellat Nadia

Institutions: Mohammed V University, Centre Hospitalier Ibn Sina

Language: English

Topic: Viral Infections and Immunology Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7168724423

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