Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH‐COPD)
Year: 2026
Type: article
Abstract: In 567 PH-COPD patients from the PVRI GoDeep Meta-Registry, ACE inhibitor use was associated with improved survival only in severe PH (PVR > 5 WU), supporting prospective trials targeting this high-risk subgroup.
Source: Pulmonary Circulation
DOI: 10.1002/pul2.70348
Authors: Athiththan Yogeswaran, Meike Fünderich, Katharina Wendlandt, Jeffrey S. Annis, Evan Brittain, Christina A. Eichstaedt, Ekkehard Grünig, Hector R. Cajigas, Robert Frantz, Andrew J. Sweatt, Roham T. Zamanian, Friedrich Grimminger, Jochen Wilhelm, Hossein‐Ardeschir Ghofrani, Khodr Tello, Werner Seeger
Institutions: German Center for Lung Research, Universities of Giessen and Marburg Lung Center, Cardio-Pulmonary Institute, Charité – Universitätsmedizin Berlin, Vanderbilt University Medical Center, Heidelberg University, University Hospital Heidelberg, Mayo Clinic, Stanford Medicine, Stanford University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,310
Funders: Brown University, University of Minnesota, Cleveland Clinic, Fondazione IRCCS Policlinico San Matteo, Johns Hopkins University, University of Pittsburgh, University of Cincinnati, Uniwersytet Jagielloński Collegium Medicum, Children’s Hospital of Wisconsin Research Institute, Murdoch Children's Research Institute, Houston Methodist Hospital, Cardiovascular Medical Research and Education Fund, Amsterdam University Medical Centers, National Institute for Health and Care Research, Imperial College London, Monash University, Universidad Nacional de La Plata, National and Kapodistrian University of Athens, Humboldt-Universität zu Berlin, Aristotle University of Thessaloniki, RWTH Aachen University, Freie Universität Berlin, Universität zu Köln, Universidad de Córdoba, Karl-Franzens-Universität Graz, Universitätsspital Zürich, Medizinische Universität Graz, Deutsches Zentrum für Lungenforschung, Universitätsklinikum Köln, Instituto Nacional de Cardiología - Ignacio Chávez, Fiona Stanley Hospital, Cardio-Pulmonary Institute, Houston Methodist Research Institute, China-Japan Friendship Hospital
Award: G7537704143
OpenAlex ID: W7168751417