Age-Stratified Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Heart Failure
Year: 2026
Type: article
Study design: Observational Study
Abstract: BACKGROUND: ) slope, in patients aged ≥80 years with heart failure (HF) remains unclear. OBJECTIVES: The study evaluated the age-stratified prognostic value of CPET parameters for adverse outcomes in patients with HF. METHODS: In this retrospective multicenter cohort study, we included 830 patients with HF who underwent CPET. The primary outcome was a composite of all-cause death or HF hospitalization within 3 years. CPET parameters were examined in 3 age groups: 20 to 64, 65 to 79, and ≥80 years. RESULTS: slope was comparable across age groups (20-64 years: 0.64 [0.56-0.72], 65-79 years: 0.68 [0.60-0.76], ≥80 years: 0.68 [0.55-0.81]). CONCLUSIONS: was most pronounced in older patients with HF, highlighting the importance of CPET-based risk stratification in this population.
Source: JACC Advances
Authors: Ken Ogura, Kentaro Kamiya, Nobuaki Hamazaki, Emi Maekawa, Chiharu Noda, Momoko Ikeda, Koshi Suzuki, Honoka Mibe, Eishin Konishi, Kohei Matsuda, Kaoru Sato, Takashi Miki, Keisuke Kida, Norio Suzuki, Takeo Fujino, Shoei Yamamoto, Takenori Ikoma, Yusuke Mizuno, Ichiro Matsumoto, Shinjiro Miyazaki, Taisuke Nakade, Yuya Matsue
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,936
OpenAlex ID: W7168774185