Work

Refractory hypoxemia following mitral valve edge-to-edge repair: why is it so refractory?

Year: 2026

Type: article

Abstract: ) ruled out common pulmonary causes. Postoperative transthoracic echocardiography (TTE) revealed a right-to-left shunt via an iASD, which was promptly closed percutaneously, resulting in rapid resolution of hypoxemia. This report highlights that severe hypoxemia following successful TEER should trigger a suspicion of a RLS, especially in patients receiving mechanical ventilation with positive end-expiratory pressure (PEEP) or anemia. Early recognition and consideration of defect closure is essential when hypoxemia is refractory to conventional ventilatory maneuvers.

Source: Journal of Cardiothoracic Surgery

DOI: 10.1186/s13019-026-04586-9

Authors: Liming Yang, Jiantong Shen, Shihong Wen

Institutions: Sun Yat-sen University, The First Affiliated Hospital, Sun Yat-sen University, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University

Language: English

Topic: Cardiovascular and Diving-Related Complications

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,890