High-gain and broadband in vivo amplifiers enabled by matched materials

Year: 2026

Type: article

Abstract: , a bandwidth above 600 Hz at 0.6 V, and an ultralow power consumption down to 0.57 nW at 0.2 V. We further demonstrate in vivo amplification of mouse electrocorticographic (ECoG) signal with good biocompatibility and superior signal quality. This work establishes a general material-device-circuit framework and design guidelines for OECT-based amplifiers.

Source: Nature Communications

DOI: 10.1038/s41467-026-75627-z

Institutions: Peking University, Tsinghua University, Dresden Integrated Center for Applied Physics and Photonic Materials, Technische Universität Dresden

Language: English

Topic: Analog and Mixed-Signal Circuit Design

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $6,990

Funders: National Natural Science Foundation of China, Natural Science Foundation of Beijing Municipality, Beijing Nova Program

Awards: G2865586656, G377519177, G6503459458, G689797374

OpenAlex ID: W7168923215