Figure S12 from Early ctDNA Stratifies Survival in Locally Advanced and Oligometastatic Lung Cancer Treated with Radiotherapy
Year: 2026
Type: other
Abstract: Supplementary Figure 12: Forest plot of multivariate cox proportional hazards regression analysis comparing the prognostic value of ctFE and Max VAF using burden-based stratification in the LA-WU cohort at pre- and mid-treatment timepoints. Hazard ratios for ctFE and Max VAF are shown as squares; horizontal bars denote 95% CIs. Low ctFE: ctFE ≤0.016411, High ctFE: ctFE >0.016411; Low Max VAF: Max VAF ≤0.0138, High Max VAF: Max VAF >0.0138. CI, confidence interval; ctFE, circulating tumor fraction estimate; HR, hazard ratio; LA-WU, locally advanced NSCLC cohort from Washington University (n = 24); Max VAF, maximum variant allele frequency; OS, overall survival; PFS, progression-free survival.
Authors: Ayesha Hashmi, Jessica Linford, Pradeep S. Chauhan, Kaushal Parikh, Malvika Pillai, John Guittar, Rotem Ben-Shachar, Jyoti Patel, Halla Nimeiri, Matteo Bergsagel, Nicholas P. Semenkovich, Sean S. Park, Kenneth R. Olivier, Dawn Owen, David M. Routman, Katie N. Lee, Alexander D. Sherry, Aaron S. Mansfield, Daniel Morgensztern, Ramaswamy Govindan, Clifford G. Robinson, Carmen Bergom, Saiama N. Waqar, Pamela P. Samson, Bruna Pellini, Gregory R. Vlacich, Aadel A. Chaudhuri
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W7169508592
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