Work

Molecular identification of toxin-antitoxin system genes and their relationship with biofilm formation among clinical isolates of Escherichia coli obtained from hospitalized and outpatients in educational hospitals in Ahvaz, Iran

Year: 2026

Type: article

Abstract: Background: biofilms are the source of both urinary tract infections and bacteremia. Objectives: . Materials and methods: isolates were tested for biofilm formation by microtiter plate assay and the presence of several TA systems such as MazF, RelE, hipA, ccdB, and MqsR. Results: isolates produced biofilms. The results revealed that 75 (75%), 80 (80%), 81 (81%), 58 (58%), and 51 (51%) of the isolates contained mazF, ccdB, relE, mqsR, and hipA TA loci, respectively. Conclusions: strains. The results demonstrated that the TA system is related with biofilm development.

Source: PubMed

DOI: 10.3205/dgkh000665

Authors: Yousefi Avarvand, Arshid, Saki, Morteza, Moradi, Melika, Ekrami, Alireza, Akrami, Sousan

Institutions: Ahvaz Jundishapur University of Medical Sciences, Tehran University of Medical Sciences

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Ahvaz Jundishapur University of Medical Sciences