Efficacy and safety of endoscopy-specific dual-channel supraglottic airways for upper gastrointestinal endoscopic and transesophageal instrumentation procedures: a systematic review and meta-analysis
Year: 2026
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: Background: Gastro™ Airway and the Jcerity Endoscoper™ Airway, are designed to maintain ventilation while permitting passage of an endoscope or transesophageal probe through a separate procedural channel. Nevertheless, their comparative efficacy and safety remain uncertain across heterogeneous procedures and comparator strategies. Methods: We conducted a systematic review and meta-analysis of randomized controlled trials comparing endoscopy-specific dc-SGAs with endotracheal tubes, other placed airway or access devices, or non-invasive oxygen therapy during upper gastrointestinal endoscopic or transesophageal instrumentation procedures. Observational studies were summarized narratively but were not included in pooled analyses. Results: Fifteen studies were included, including 13 randomized controlled trials involving 2,481 participants in the quantitative synthesis and 2 observational studies summarized narratively. Endoscopy-specific dc-SGAs showed comparable first-attempt airway device and endoscope/probe insertion success to comparator strategies and shortened airway device insertion time. Effects on endoscope/probe insertion time and endoscopist satisfaction were inconsistent and varied across comparator types. dc-SGAs reduced intraoperative hypoxemia, mainly in comparisons with non-invasive oxygen therapy. Postoperative sore throat showed a comparator-dependent pattern, with fewer events compared with endotracheal tubes but more events compared with non-invasive oxygen therapy. Conclusion: Endoscopy-specific dc-SGAs may represent a feasible intermediate airway strategy for selected patients undergoing upper gastrointestinal endoscopic and transesophageal instrumentation procedures. They may improve airway placement efficiency and, compared with non-invasive oxygen therapy, reduce hypoxemia; however, these potential benefits should be interpreted in light of comparator-dependent throat discomfort, procedure heterogeneity, and the low-to-moderate certainty of evidence. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251182546, identifier [CRD420251182546].
Source: Frontiers in Medicine
Authors: Yanqin Mi, Zhengfang Qi, Yan Wei, Yatao Liu, Zhaohui Gao
Institutions: Lanzhou University, First Hospital of Lanzhou University
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7169561911